%0 Journal Article %T Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study %A Alberto Martini %A Anasuya Hazra %A Charles A. Mebus %A Christine Alvey %A Daniel J. Kingsbury %A Daniel J. Lovell %A Elzbieta Smolewska %A Gerd Horneff %A Hermine I. Brunner %A Ivan Foeldvari %A Manisha Lamba %A Min Wang %A Nicolino Ruperto %A Nikolay Tzaribachev %A Ricardo Suehiro %A Richard K. Vehe %A Rong Wang %A Sriram Krishnaswami %A Thomas C. Stock %A Zbigniew Zuber %A for the Pediatric Rheumatology International Trials Organization (PRINTO) %A the Pediatric Rheumatology Collaborative Study Group (PRCSG) %J Archive of "Pediatric Rheumatology Online Journal". %D 2017 %R 10.1186/s12969-017-0212-y %X The online version of this article (10.1186/s12969-017-0212-y) contains supplementary material, which is available to authorized users %K Janus kinase inhibitor %K Juvenile idiopathic arthritis %K Tofacitinib %K Pediatric %K Pharmacokinetics %K Safety %K Dosing %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745974/