%0 Journal Article
%T Protective immunity against influenza in HLA-A2 transgenic mice by modified vaccinia virus Ankara vectored vaccines containing internal influenza proteins
%A Antonio Siccardi
%A Bruno Garulli
%A Elisa Soprana
%A Ester Sciaraffia
%A Francesco Gubinelli
%A Giuseppina Di Mario
%A Isabella Donatelli
%A Maddalena Panigada
%A Maria R. Castrucci
%A Marzia Facchini
%A Valentina Bernasconi
%J Archive of "Pathogens and Global Health".
%D 2017
%R 10.1080/20477724.2016.1275465
%X Background: The emergence of novel strains of influenza A viruses with hemagglutinins (HAs) that are antigenically distinct from those circulating in humans, and thus have pandemic potential, pose concerns and call for the development of more broadly protective influenza vaccines. In the present study, modified vaccinia virus Ankara (MVA) encoding internal influenza antigens were evaluated for their immunogenicity and ability to protect HLA-A2.1 transgenic (AAD) mice from infection with influenza viruses
%K Influenza virus
%K vaccine
%K internal proteins
%K MVA vector
%K transgenic mice
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5375616/