%0 Journal Article %T Modulatory Effect of Carotenoid Supplement Constituting Lutein and Zeaxanthin (10:1) on Anti-oxidant Enzymes and Macular Pigments Level in Rats %A Ashok Godavarthi %A Jayashree Madhavan %A MK Priya %A Sundaram Chandrasekharan %J Archive of "Pharmacognosy Magazine". %D 2018 %R 10.4103/pm.pm_340_17 %X Human eye is constantly exposed to different wavelengths and intensities of light. Oxidative stress results in distinct changes to retinal organs and tissues. Macular pigments (lutein and zeaxanthin), present in the central macular region, provide protection from photodamages by absorption of high energy blue light and also by virtue of their anti-oxidant activity. Ocular phototoxicity is thus prevented by our efficient anti-oxidant system, in both young and old. One of the best commercial sources of pure lutein and zeaxanthin is Marigold flowers %K Anti-oxidant enzymes %K dietary carotenoid supplement %K macular pigments in serum and macula %K retinal pigment epithelium %K trans-Lutein %K trans-Zeaxanthin %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909327/