%0 Journal Article %T Association between anxious distress in a major depressive episode and bipolarity %A Hiroko Sugawara %A Jun Ishigooka %A Katsuji Nishimura %A Ken Inada %A Mamoru Hashimoto %A Minoru Takebayashi %A Takahiro Tsutsumi %J Archive of "Neuropsychiatric Disease and Treatment". %D 2019 %R 10.2147/NDT.S188947 %X Mixed features in a major depressive episode (MDE) predict bipolar disorder (BD). The mixed features specifier included in the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) could be restrictive because it excludes the symptoms common to both mania/hypomania and depression, including psychomotor agitation. On the other hand, an anxious distress (ANXD) specifier has also been introduced in the DSM-5, and psychomotor agitation has been defined as a severity of ANXD. In this study, we retrospectively investigated the association between presence of ANXD in an MDE and bipolarity %K anxious distress %K mixed features %K major depressive episode %K bipolarity %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339637/