%0 Journal Article
%T Resting-state fMRI study of acute migraine treatment with kinetic oscillation stimulation in nasal cavity
%A Jan-Erik Juto
%A Rolf Hallin
%A Tie-Qiang Li
%A Yanlu Wang
%J Archive of "NeuroImage : Clinical".
%D 2016
%R 10.1016/j.nicl.2016.08.014
%X Kinetic oscillatory stimulation (KOS) in the nasal cavity is a non-invasive cranial nerve stimulation method with promising efficacy for acute migraine and other inflammatory disorders. For a better understanding of the underlying neurophysiological mechanisms of KOS treatment, we conducted a resting-state functional magnetic resonance imaging (fMRI) study of 10 acute migraine patients and 10 normal control subjects during KOS treatment in a 3 T clinical MRI scanner. The fMRI data were first processed using a group independent component analysis (ICA) method and then further analyzed with a voxel-wise 3-way ANOVA modeling and region of interest (ROI) of functional connectivity metrics
%K Kinetic oscillatory stimulation (KOS)
%K Migraine
%K Autonomic nervous system (ANS)
%K Resting-state fMRI
%K Intrinsic functional activity
%K Independent component analysis (ICA)
%K 3-Way ANOVA
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008046/