%0 Journal Article %T Sleep apnea: Altered brain connectivity underlying a working-memory challenge %A Andrea Falini %A Antonella Iadanza %A Luigi Ferini-Strambi %A Nicola Canessa %A Sara Marelli %A Stefano F. Cappa %A Vincenza Castronovo %J Archive of "NeuroImage : Clinical". %D 2018 %R 10.1016/j.nicl.2018.03.036 %X Obstructive sleep apnea (OSA) is characterized by the frequent presence of neuro-cognitive impairment. Recent studies associate cognitive dysfunction with altered resting-state brain connectivity between key nodes of the executive and default-mode networks, two anti-correlated functional networks whose strength of activation increases or decreases with cognitive activity, respectively. To date no study has investigated a relationship between cognitive impairment in OSA and brain connectivity during an active working-memory challenge. We thus investigated the effect of OSA on working-memory performance and underlying brain connectivity %K Obstructive sleep apnea %K Executive functions %K Working-memory %K fMRI %K Cognitive disorders %K Brain connectivity %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051941/