%0 Journal Article
%T The effective connectivity of the seizure onset zone and ictal perfusion changes in amygdala kindled rhesus monkeys
%A Cindy Casteels
%A Elsie Premereur
%A Evy Cleeren
%A Karolien Goffin
%A Peter Janssen
%A Wim Van Paesschen
%J Archive of "NeuroImage : Clinical".
%D 2016
%R 10.1016/j.nicl.2016.05.020
%X Epileptic seizures are network-level phenomena. Hence, epilepsy may be regarded as a circuit-level disorder that cannot be understood outside this context. Better insight into the effective connectivity of the seizure onset zone and the manner in which seizure activity spreads could lead to specifically-tailored therapies for epilepsy
%K 99mTc-ECD
%K 99m-technetium labeled ethyl cysteinate diethylester
%K EM-fMRI
%K electrical microstimulation during functional magnetic resonance imaging
%K MION
%K monocrystalline iron oxide nanoparticle
%K MTLE
%K mesial temporal lobe epilepsy
%K PSC
%K percent signal change
%K SISCOM
%K subtraction Ictal SPECT co-registered to MRI
%K SPECT
%K single photon emission computed tomography
%K VOI
%K Volume-Of-Interest Ictal single photon emission computed tomography
%K Electrical microstimulation
%K Functional magnetic resonance imaging
%K Amygdala kindling
%K Mesial temporal lobe epilepsy
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959940/