%0 Journal Article
%T Large next-generation sequencing gene panels in genetic heart disease: yield of pathogenic variants and variants of unknown significance
%A F. H. M. van Lint
%A H. Bikker
%A I. Christiaans
%A M. Alders
%A O. R. F. Mook
%A R. H. Lekanne dit Deprez
%J Archive of "Netherlands Heart Journal".
%D 2019
%R 10.1007/s12471-019-1250-5
%X Genetic heterogeneity is common in inherited cardiac diseases. Next-generation sequencing gene panels are therefore suitable for genetic diagnosis. We describe the results of implementation of cardiomyopathy and arrhythmia gene panels in clinical care
%K Next-generation sequencing
%K Variants of unknown significance
%K Cardiogenetic
%K Gene panel
%K Detection rate
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533346/