%0 Journal Article
%T Evaluation of gene panels for inherited cardiac disease¡ªis less more?
%A A. F. Baas
%A D. Dooijes
%A M. Siemelink
%J Archive of "Netherlands Heart Journal".
%D 2019
%R 10.1007/s12471-019-1279-5
%X In this issue of the Netherlands Heart Journal, van Lint et al. describe the yield of diagnostic next-generation sequencing (NGS) gene panels for cardiomyopathies and primary arrhythmia syndromes [1]. Historically, cardiogenetic testing was performed using Sanger sequencing, usually in a gene-by-gene fashion each requiring many months. In 2012, diagnostic NGS testing was introduced in the Netherlands, enabling rapid analysis of large gene panels simultaneously (e.£¿g. over 50 genes in 2¨C3 months), drastically improving cardiogenetic diagnostics
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533339/