%0 Journal Article %T Slow sleep spindle and procedural memory consolidation in patients with major depressive disorder %A Masaki Nishida %A Toru Nishikawa %A Yusaku Nakashima %J Archive of "Nature and Science of Sleep". %D 2016 %R 10.2147/NSS.S100337 %X Evidence has accumulated, which indicates that, in healthy individuals, sleep enhances procedural memory consolidation, and that sleep spindle activity modulates this process. However, whether sleep-dependent procedural memory consolidation occurs in patients medicated for major depressive disorder remains unclear, as are the pharmacological and physiological mechanisms that underlie this process %K depression %K memory consolidation %K motor skill %K polysomnography %K sleep spindle %K thalamocortical network %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734800/