%0 Journal Article
%T Neuroanatomical correlates of prion disease progression - a 3T longitudinal voxel-based morphometry study
%A Diana Caine
%A Enrico De Vita
%A Gerard R Ridgway
%A Hans Rolf Jager
%A Harpreet Hyare
%A John Collinge
%A John S Thornton
%A Marie-Claire Porter
%A Mark J White
%A Peter Rudge
%A Simon Mead
%A Tarek A Yousry
%J Archive of "NeuroImage : Clinical".
%D 2017
%R 10.1016/j.nicl.2016.10.021
%X MRI has become an essential tool for prion disease diagnosis. However there exist only a few serial MRI studies of prion patients, and these mostly used whole brain summary measures or region of interest based approaches. We present here the first longitudinal voxel-based morphometry (VBM) study in prion disease. The aim of this study was to systematically characterise progressive atrophy in patients with prion disease and identify whether atrophy in specific brain structures correlates with clinical assessment
%K Prion disease
%K Structural MRI
%K Longitudinal voxel based morphometry
%K 3T MRI
%K CJD
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133666/