%0 Journal Article
%T MiR-221/222 promote epithelial-mesenchymal transition by targeting Notch3 in breast cancer cell lines
%A Chun-Fa Chen
%A Frank A. E. Kruyt
%A Guo-Jun Zhang
%A Hao-Yu Lin
%A Jing-Wen Bai
%A Min Chen
%A Xiao-Long Wei
%A Xiao-Wei Dou
%A Yang Wu
%A Ying-Sheng Xiao
%A Yong-Qu Zhang
%A Yu-Zhu Qi
%A Yuan-Ke Liang
%J Archive of "NPJ Breast Cancer".
%D 2018
%R 10.1038/s41523-018-0073-7
%X miR-221/222 have an inverse correlation with Notch3 in breast cancer cells. a qRT-PCR analysis of Notch3 mRNA expression in breast cancer cell lines. b Endogenous Notch3 full length (FL) and the intracellular domain (ICD), ER¦Á, E-cadherin, and Vimentin protein levels in breast cancer cell lines. c, d Databases to predict miR-221/222 target genes and sequence alignment of the human miR-221 and miR-222 seed regions with Notch3 3¡äUTR, which contains predicted miR-221/222 binding site. e qRT-PCR analysis of miR-221/222 expression in breast cancer cell line
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079079/