%0 Journal Article
%T Improved cerebral microbleeds detection using their magnetic signature on T2*-phase-contrast: A comparison study in a clinical setting
%A Ali Bouyahia
%A Anne Bertrand
%A Bruno Law-ye
%A Carole Dufouil
%A Christine Delmaire
%A Didier Dormont
%A Fatma Ouamer
%A Ludovic de Rochefort
%A Marie Chupin
%A Nadya Pyatigorskaya
%A Nathalie Thiery
%A Takoua Kaaouana
%J Archive of "NeuroImage : Clinical".
%D 2017
%R 10.1016/j.nicl.2016.08.005
%X In vivo detection of cerebral microbleeds (CMBs) from T2* gradient recalled echo (GRE) magnitude image suffers from low specificity, modest inter-rater reproducibility and is biased by its sensitivity to acquisition parameters. New methods were proposed for improving this identification, but they mostly rely on 3D acquisitions, not always feasible in clinical practice. A fast 2D phase processing technique for computing internal field maps (IFM) has been shown to make it possible to characterize CMBs through their magnetic signature in routine clinical setting, based on 2D multi-slice acquisitions. However, its clinical interest for CMBs identification with respect to more common images remained to be assessed. To do so, systematic experiments were undertaken to compare the ratings obtained by trained observers with several image types, T2* magnitude, Susceptibility Weighted Imaging reconstructions (SWI) and IFM built from the same T2*-weighted acquisition
%K Microbleeds
%K Magnetic susceptibility
%K Phase MRI
%K SWI
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435598/