%0 Journal Article %T Breast cancer chemoprevention pharmacogenomics: Deep sequencing and functional genomics of the ZNF423 and CTSO genes %A D. Lawrence Wickerham %A Daniel J. Schaid %A Duan Liu %A Erin Carlson %A James N. Ingle %A Jared Evans %A Joanna Biernacka %A Krishna Kalari %A Liewei Wang %A Matthew P. Goetz %A Michiaki Kubo %A Ming-Fen Ho %A Mohan Liu %A Richard M. Weinshilboum %A Steven E. Scherer %A Vivien Yee %J Archive of "NPJ Breast Cancer". %D 2017 %R 10.1038/s41523-017-0036-4 %X The SERM-dependent, SNP-dependent ¡°reversal¡± of estradiol induction of ZNF423 and BRCA1 expression in LCLs. a Estradiol (E2) and 4-hydroxytamoxifen (4OH-TAM) dose response curves for expression of ZNF423 (a) and BRCA1 (b) in LCLs with known genotypes for the ZNF423 intron 2 rs9940645 SNP. Values are mean£¿¡À£¿SEM for 8 determinations. (modified from Fig. 3, Ingle et al. Cancer Discovery 20136 %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5566425/