%0 Journal Article
%T DNA methylation analysis of secreted frizzled-related protein 2 gene for the early detection of colorectal cancer in fecal DNA
%A Hadi Babaei
%A Mohsen Mohammadi
%A Rasoul Salehi
%J Archive of "Nigerian Medical Journal : Journal of the Nigeria Medical Association".
%D 2016
%R 10.4103/0300-1652.188357
%X The early detection of colorectal cancer (CRC) with high sensitivity screening is essential for the reduction of cancer-specific mortality. Abnormally methylated genes that are responsible for the pathogenesis of cancers can be used as biomarkers for the detection of CRC. The methylation status of the secreted frizzled-related protein 2 (SFRP2) gene was evaluated for their use as a marker in the noninvasive detection of CRC
%K Colorectal cancer
%K DNA methylation
%K secreted frizzled-related protein
%K stool DNA test
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995817/