%0 Journal Article
%T Lanthanide-Doped Nanoparticles for Diagnostic Sensing
%A Aeju Lee
%A Min Lin
%A Song Yeul Lee
%A Yong Il Park
%J Archive of "Nanomaterials".
%D 2017
%R 10.3390/nano7120411
%X Lanthanide-doped nanoparticles exhibit unique optical properties, such as a long luminescence lifetime (up to several milliseconds), sharp emission peaks, and upconversion luminescence over the range of wavelengths from near-infrared to visible. Exploiting these optical properties, lanthanide-doped nanoparticles have been widely utilized for cellular and small animal imaging with the absence of background autofluorescence. In addition, these nanoparticles have advantages of high signal-to-noise ratio for highly sensitive and selective diagnostic detection. In this review, we summarize and discuss recent progress in the development of highly sensitive diagnostic methods using lanthanide-doped nanoparticles. Combined with a smartphone, portable luminescence detecting platforms could be widely applied in point-of-care tests
%K lanthanide
%K upconversion
%K nanoparticles
%K diagnostics
%K sensing
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746901/