%0 Journal Article %T Help cure Parkinson¡¯s disease: please don¡¯t waste the Golden Year %A Robert A. Hauser %J Archive of "NPJ Parkinson's Disease". %D 2018 %R 10.1038/s41531-018-0065-1 %X Relationship between time of diagnosis, need for symptomatic therapy and the opportunity for a patient to participate in an early PD disease modifying therapy trial. a The patient is diagnosed with early PD soon after the onset of motor symptoms and is enrolled in a disease modifying clinical trial. The ¡°Golden Year¡± is the time from when a diagnosis of early PD can be made and the time when symptomatic therapy is needed. The red dashed line represents the potential disease slowing that might be associated with a disease modifying therapy. b The patient has waited to be evaluated until they need symptomatic therapy. They are no longer eligible to particpate in a disease modifying clinical trial and the Golden Year has been wasted. c The patient is diagnosed with early PD soon after the onset of motor symptoms but is immediately placed on symptomatic therapy. The patient is no longer eligible to participate in a disease modifying clinical trial and the Golden Year has been waste %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156591/