%0 Journal Article
%T Extracellular vesicle-mediated EBAG9 transfer from cancer cells to tumor microenvironment promotes immune escape and tumor progression
%A Kazuhiro Ikeda
%A Kuniko Horie-Inoue
%A Satoshi Inoue
%A Toshiaki Miyazaki
%A Wataru Sato
%J Archive of "Oncogenesis".
%D 2018
%R 10.1038/s41389-017-0022-6
%X a Representative genitourinary organs. Ebag9KO mice were crossed with TRAMP mice to generate Ebag9KO;TRAMP(+) and control Ebag9WT;TRAMP(+) mice. Genitourinary organs were dissected from these male mice at 1 year old. Scale bar, 1£¿cm. b Prostate tumor development was repressed in Ebag9KO;TRAMP(+) mice. Genitourinary organ weight was measured at 1 year old. c Upregulation of Cd8 mRNA in prostate tumors generated in Ebag9KO;TRAMP(+) mice. qRT-PCR analysis of Cd8 mRNA was performed using RNAs from prostate tumors. The data are shown as mean£¿¡À£¿SD (Ebag9KO;TRAMP(+), n£¿=£¿10; Ebag9WT;TRAMP(+), n£¿=£¿17). *P£¿<£¿0.05 (two-sided Student¡¯s t-test
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833691/