%0 Journal Article
%T Vitamin K in Chronic Kidney Disease
%A Andrea Galassi
%A Mario Cozzolino
%A Michela Mangano
%A Paola Ciceri
%A Piergiorgio Messa
%A Sagar Nigwekar
%J Archive of "Nutrients".
%D 2019
%R 10.3390/nu11010168
%X Vitamin K is a composite term referring to a group of fat-soluble vitamins that function as a cofactor for the enzyme ¦Ã-glutamyl carboxylase (GGCX), which activates a number of vitamin K-dependent proteins (VKDPs) involved in haemostasis and vascular and bone health. Accumulating evidence demonstrates that chronic kidney disease (CKD) patients suffer from subclinical vitamin K deficiency, suggesting that this represents a population at risk for the biological consequences of poor vitamin K status. This deficiency might be caused by exhaustion of vitamin K due to its high requirements by vitamin K-dependent proteins to inhibit calcification
%K vitamin K
%K CKD
%K vascular calcification
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356438/