%0 Journal Article %T Adaptive resistance to anti-PD1 therapy by Tim-3 upregulation is mediated by the PI3K-Akt pathway in head and neck cancer %A Gulidanna Shayan %A Jing Li %A Lawrence P. Kane %A Nicole Schmitt %A Raghvendra Srivastava %A Robert L. Ferris %J Archive of "Oncoimmunology". %D 2017 %R 10.1080/2162402X.2016.1261779 %K Head and neck cancer %K immunotherapy %K monoclonal antibody %K PD-1 %K Tim-3 %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283618/