%0 Journal Article %T Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with dietŠ\induced obesity %A A. K. J. Gradel %A H. H. F. Refsgaard %A J. Lykkesfeldt %A P. B. Brockhoff %A T. Porsgaard %A T. Seested %J Archive of "Obesity Science & Practice". %D 2019 %R 10.1002/osp4.326 %X Obesity is associated with delayed insulin absorption upon subcutaneous (s.c.) dosing in humans. The aim of this study was to investigate whether alterations in depot structure and kinetics of the s.c. injection depot contribute to this delay %K Injection depot %K insulin pharmacokinetics %K obesity %K subcutaneous administration %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587326/