%0 Journal Article
%T Maternal overnutrition by hypercaloric diets programs hypothalamic mitochondrial fusion and metabolic dysfunction in rat male offspring
%A Alberto Camacho
%A Ana Laura de la Garza
%A Aracely Garcia-Garcia
%A Armando R. Tovar
%A Elena Zambrano
%A Humberto Rodriguez-Rocha
%A Ivan Torre-Villalvazo
%A Jennifer Saville
%A Juan Carlos Corona-Castillo
%A Lizeth Fuentes-Mera
%A Luis A. Reyes-Castro
%A Maria Fuller
%A Robbi E. Cardenas-Perez
%A Rocio Ortiz-Lopez
%J Archive of "Nutrition & Metabolism".
%D 2018
%R 10.1186/s12986-018-0279-6
%X Effect of nutritional programming on dams and male offspring weight. a) Animal model. We fed female Wistar rats for 9 weeks according to the schedule to promote maternal programming or we fed offspring with hypercaloric diet exposure after weaning. b) Maternal body weight was followed for 6 weeks (pre-mating, mating and gestation) (Control n£¿=£¿7, HFD n£¿=£¿7, CAF n£¿=£¿6 and HSD n£¿=£¿4). c) Birth weight of offspring at day 0. d) Body weight after weaning for Control versus HFD-C, CAF-C, HSD-C for maternal programming groups, where HFD, CAF and HSD are maternal diet and C is control chow diet of offspring. e) Body weight after weaning for Control versus offspring fed with HFD, CAF and HSD after weaning (HFD-HFD, CAF-CAF, HSD-HSD groups). Data are means ¡À SD. *p£¿<£¿0.05, **p£¿<£¿0.01 and ***p£¿<£¿0.00
%K Maternal overnutrition
%K Diet induced obesity (DIO)
%K Hypothalamus
%K Mitochondria
%K Mitochondria dynamics
%K Fusion
%K Fission
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987395/