%0 Journal Article
%T FIBP knockdown attenuates growth and enhances chemotherapy in colorectal cancer via regulating GSK3¦Â-related pathways
%A Da-Jian Zhu
%A Ling-Jun Wang
%A Lu Lu
%A Ming-Qing Wang
%A Rong Hu
%A Shao-Xiang Xian
%A Shi-Hao Ni
%A Wei Xiao
%A Wen-Bo Niu
%A Wen-Jun Feng
%A Yan-Feng Huang
%A Yi Yang
%A Yu-Sheng Huang
%A Zeng-Yan Huang
%J Archive of "Oncogenesis".
%D 2018
%R 10.1038/s41389-018-0088-9
%X a The hazard risk (HR) distribution of 56 genes with high expression and association with poor prognosis based on TCGA raw data from cBioPortal. The filtering criteria are p£¿<£¿0.05 and HR£¿>£¿0. b Venn diagram showing that FIBP, HSFY1, and PPM1K are simultaneously present in both the set of genes with a high HR and the set of genes downregulated by curcumin. c Expression of FIBP was higher in CRC specimens with chemoresistance (CR) than in chemosensitive tissue. n£¿=£¿10 for the CRC group, and n£¿=£¿6 for the CRC with CR group. d Representative immunochemistry staining results in tumors with/without chemoresistance (magnification, ¡Á200). e Kaplan¨CMeier survival curves according to FIBP levels. *p£¿<£¿0.05 CRC vs. CRC with C
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167373/