%0 Journal Article
%T Lentivirus-mediated overexpression of HSDL2 suppresses cell proliferation and induces apoptosis in cholangiocarcinoma
%A Bin-Quan Wu
%A Deng-Yong Zhang
%A Pei Zhang
%A Pei-Yuan Cui
%A Wan-Liang Sun
%A Xiang Ma
%A Zheng Lu
%A Zhong Liu
%J Archive of "OncoTargets and therapy".
%D 2018
%R 10.2147/OTT.S176410
%X Cholangiocarcinoma (CCA) is a malignant tumor of the bile duct epithelium, including intrahepatic, perihilar, and distal CCA based on anatomical location. Hydroxysteroid dehydrogenase-like 2 (HSDL2) belongs to the SDR subfamily of oxidoreductases, and it is involved in glioma oncogenesis, as it can promote cell proliferation and inhibit cell apoptosis. The purpose of this study was to explore the underlying molecular mechanisms of HSDL2 in the process of CCA
%K cholangiocarcinoma
%K CCA
%K HSDL2
%K lentivirus
%K proliferation
%K apoptosis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200078/