%0 Journal Article
%T A Healthy Dietary Pattern Reduces Lung Cancer Risk: A Systematic Review and Meta-Analysis
%A Jianjun Han
%A Jianning Li
%A Yanlai Sun
%A Zengjun Li
%A Zhenxiang Li
%J Archive of "Nutrients".
%D 2016
%R 10.3390/nu8030134
%X Background: Diet and nutrients play an important role in cancer development and progress; a healthy dietary pattern has been found to be associated with several types of cancer. However, the association between a healthy eating pattern and lung cancer risk is still unclear. Objective: Therefore, we conducted a systematic review with meta-analysis to evaluate whether a healthy eating pattern might reduce lung cancer risk. Methods: We identified relevant studies from the PubMed and Embase databases up to October 2015, and the relative risks were extracted and combined by the fixed-effects model when no substantial heterogeneity was observed; otherwise, the random-effects model was employed. Subgroup and publication bias analyses were also performed. Results: Finally, eight observational studies were included in the meta-analysis. The pooled relative risk of lung cancer for the highest vs. lowest category of healthy dietary pattern was 0.81 (95% confidence interval, CI: 0.75¨C0.86), and no significant heterogeneity was detected. The relative risks (RRs) for non-smokers, former smokers and current smokers were 0.89 (95% CI: 0.63¨C1.27), 0.74 (95% CI: 0.62¨C0.89) and 0.86 (95% CI: 0.79¨C0.93), respectively. The results remained stable in subgroup analyses by other confounders and sensitivity analysis. Conclusions: The results of our meta-analysis suggest that a healthy dietary pattern is associated with a lower lung cancer risk, and they provide more beneficial evidence for changing the diet pattern in the general population
%K nutrition
%K dietary pattern
%K lung cancer
%K risk factors
%K meta-analysis
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808863/