%0 Journal Article
%T A dual role of miR-22 modulated by RelA/p65 in resensitizing fulvestrant-resistant breast cancer cells to fulvestrant by targeting FOXP1 and HDAC4 and constitutive acetylation of p53 at Lys382
%A Bo Wang
%A Dongping Li
%A Emily Carpenter
%A Jody Filkowski
%A Megan Malach
%A Olga Kovalchuk
%A Quinn Storozynsky
%A Rocio Rodriguez-Juarez
%J Archive of "Oncogenesis".
%D 2018
%R 10.1038/s41389-018-0063-5
%X a Total RNA isolated from the 182R-6 cell line and its parental S05 cell line was subjected to qRT-PCR analysis using a primer set for hsa-miR-22. RNU6-2 was used as a reference gene to normalize miR-22 expression. b Whole cellular lysates prepared from S05 and 182R-6 cells were subjected to western blot analysis using antibodies to either AGO2 or Dicer or Drosha; actin served as a loading control. c S05 and 182R-6 cells grown to 60¨C75% confluency on glass coverslips were fixed with 4% paraformaldehyde and permeabilized with ice-cold methanol. Immunofluorescence staining was performed using antibodies to either AGO2 or Dicer, as described in the ¡°Methods¡± section. * indicates p£¿<£¿0.0
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064715/