%0 Journal Article
%T Exploratory Analysis for the Evaluation of Estimated Glomerular Filtration Rate, Cholesterol and Triglycerides after Switching from Tenofovir/Emtricitabine plus Atazanavir/Ritonavir (ATV/r) to Abacavir/Lamivudine plus ATV/r in Patients with Preserved Renal Function
%A Carlo Torti
%A Daria Gotti
%A Eugenia Quiros-Roldan
%A Filippo Castelnuovo
%A Franco Maggiolo
%A Giuseppe Lapadula
%A Laura Sighinolfi
%A Maria Concetta Postorino
%A Massimo Di Pietro
%A Nicola Mazzini
%A Nicoletta Ladisa
%A Silvia Lorenzotti
%A Simona Di Giambenedetto
%A and The MASTER Study Group
%J Archive of "The Open AIDS Journal".
%D 2016
%R 10.2174/1874613601610010136
%X Renal toxicity due to tenofovir (TDF) has been largely described in patients with HIV infection. However, other antiretroviral drugs (such as atazanavir [ATV], especially when boosted by ritonavir, ATV/r) could perpetuate some degrees of renal impairment with or without TDF co-administration. Also, possible benefits of stopping TDF in patients without renal diseases is not well known. This study aimed at exploring evolution of renal function and lipid profile after switching from tenofovir/emtricitabine (TDF/FTC) to abacavir/lamivudine (ABC/3TC), maintaining the ATV/r component of the regimen
%K Highly Active Antiretroviral Therapy
%K eGFR
%K Cholesterol
%K Nephrotoxicity
%K Tenofovir
%K Atazanavir
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968049/