%0 Journal Article %T Identification of strong intron enhancer in the heparanase gene: effect of functional rs4693608 variant on HPSE enhancer activity in hematological and solid malignancies %A Ania Hava Grushchenko-Polaq %A Arnon Nagler %A Avichai Shimoni %A Israel Vlodavsky %A Jonathan Canaani %A Katia Beider %A Margarita Mayorov %A Olga Ostrovsky %J Archive of "Oncogenesis". %D 2018 %R 10.1038/s41389-018-0060-8 %X The size of analyzed enhancer region is 440£¿bp. It includes four polymorphic SNPs: rs4693083, rs4693608, rs4693084, and rs4693609. The map represents exact location of the SNPs and nucleotide substitution. The distance between rs4693083 and rs4693608 is 40£¿bp, whereas the interval between rs4693608 and rs4693084 is 17£¿bp. Additional rs4693609 SNP is located 199£¿bp upstream of rs469308 %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023935/