%0 Journal Article %T Localized retinal degeneration secondary to Waldenstr£żm's macroglobulinemia %A Dhanashree Ratra %A Mansi Kishnani %A Vineet Ratra %J Archive of "Oman Journal of Ophthalmology". %D 2017 %R 10.4103/ojo.OJO_126_2016 %X A 52-year-old man, treated for Waldenstr£żm's macroglobulinemia (WM), continued to experience decreased vision even after 24 months. He was evaluated using multimodal imaging and electroretinography. The retina did not show any hyperviscosity changes but revealed a yellow lesion at macula with atrophic changes causing a pattern on fluorescein angiography similar to a leopard's skin. Optical coherence tomographic imaging revealed uniformly reflective material deposited in the outer retina with degeneration of outer retinal layers. Full-field electroretinography was normal, but multifocal electroretinography revealed reduced foveal responses. This case highlights the degenerative effects of long-standing immunogammopathy maculopathy in WM %K Lymphoproliferative disorder %K macroglobulinemia %K Retinal degeneration %K serous macular detachment %K subretinal deposits %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657173/