%0 Journal Article
%T Wilson¡¯s disease presenting during pregnancy: A diagnostic and
therapeutic dilemma
%A Anish Keepanasseril
%A Esha R Shanbhag
%A Jayalakshmi Durairaj
%A Mamtha Gowda
%A P Veena
%J Archive of "Obstetric Medicine".
%D 2018
%R 10.1177/1753495X17743162
%X Wilson¡¯s disease is an autosomal recessive genetic disorder affecting copper transport leading to hepatic and/or neuropsychiatric manifestations. Changes in pregnancy can mimic certain clinical features of chronic liver disease such as spider naevi, and constraints for the use of various investigation for diagnosis pose a challenge to physicians. A high index of suspicion, multi-disciplinary team approach, use of correct non-invasive testing including viral serology, autoantibodies and copper studies and ultrasonography help to diagnose most of the pre-existing, de novo or pregnancy-specific hepatological conditions. We report a case of Wilson¡¯s disease diagnosed during pregnancy and discuss the challenges in diagnosis and treatment in pregnancy
%K Gastroenterology
%K hepatology
%K high-risk pregnancy
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134349/