%0 Journal Article %T Vitamin D and the Liver¡ªCorrelation or Cause? %A Harendran Elangovan %A Jenny E. Gunton %A Jeremy T. Keane %A Rebecca A. Stokes %J Archive of "Nutrients". %D 2018 %R 10.3390/nu10040496 %X Vitamin D is becoming increasingly accepted as an important physiological regulator outside of its classical role in skeletal homeostasis. A growing body of evidence connects vitamin D with hepatic disease. This review summarises the role of vitamin D in liver homeostasis and disease and discusses the therapeutic potential of vitamin D-based treatments to protect against hepatic disease progression and to improve response to treatment. While pre-clinical experimental data is promising, clinical trials around liver diseases have mostly been under-powered, and further studies will be required to clarify whether vitamin D or vitamin D analogues have beneficial effects on liver disease %K vitamin D %K VDR %K liver fibrosis %K NAFLD %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946281/