%0 Journal Article
%T Apple polyphenol extract improves insulin sensitivity in vitro and in vivo in animal models of insulin resistance
%A Jose M. Lopez-Pedrosa
%A Jos¨¦ D. Vilchez
%A Manuel Manzano
%A Mar¨ªa D Giron
%A Natalia Sevillano
%A Nuri El-Azem
%A Rafael Salto
%A Ricardo Rueda
%J Archive of "Nutrition & Metabolism".
%D 2016
%R 10.1186/s12986-016-0088-8
%X Apple polyphenols could represent a novel nutritional approach in the management and control of blood glucose, especially in type 2 diabetics. The aim of this study was to test the therapeutic potential of an apple polyphenol extract (APE) in an insulin-resistant rat model and to determine the molecular basis of insulin sensitivity action in skeletal muscle cells
%K Apple polyphenol extract
%K Insulin sensitivity
%K Blood glucose uptake
%K Skeletal muscle
%K Diabetes
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852413/