%0 Journal Article
%T Precise identification of immunotherapeutic targets for solid malignancies using clues within the tumor microenvironment¡ªEvidence to turn on the LIGHT
%A Ajay V. Maker
%J Archive of "Oncoimmunology".
%D 2016
%R 10.1080/2162402X.2015.1069937
%X Targeted immunotherapy for solid gastrointestinal malignancies is challenging due to a lack of identified tumor antigens. Therefore, a strategy that supports and expands tumor infiltrating lymphocytes in the tumor microenvironment may allow these tumor-reactive T-cells to incite an antitumor response. Gene expression analysis of colon metastases has identified specific immunotherapeutic targets for this malignancy
%K Colon cancer
%K immunotherapy
%K gastrointestinal cancers
%K LIGHT
%K metastasis
%K Tnfsf14
%K tumor infiltrating lymphocytes
%K tumor microenvironment
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760328/