%0 Journal Article
%T The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity
%A C.G. Pellizas
%A G.A. Rabinovich
%A M.M. Montesinos
%A V.A. Alamino
%J Archive of "Oncoimmunology".
%D 2016
%R 10.1080/2162402X.2015.1064579
%X Dendritic cell (DC) cancer vaccines have shown limited clinical benefit. Thus, the identification of signals and molecular pathways that potentiate the immunogenicity of DCs has become a major challenge in cancer research. Our studies demonstrate that triiodothyronine endows DCs with enhanced ability to stimulate cytotoxic T-cell responses with implications in DC-based immunotherapy
%K Cancer vaccination
%K dendritic cell
%K immunotherapy
%K thyroid hormone
%K triiodothyronine
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760281/