%0 Journal Article
%T On the Cellular and Molecular Mechanisms of Drug-Induced Gingival Overgrowth
%A Albert Ram¨ªrez-R¨¢miz
%A Eduard Lahor-Soler
%A Jaume Miranda-Rius
%A Llu¨ªs Brunet-LLobet
%J Archive of "The Open Dentistry Journal".
%D 2017
%R 10.2174/1874210601711010420
%X Gingival overgrowth has been linked to multiple factors such as adverse drug effects, inflammation, neoplastic processes, and hereditary gingival fibromatosis. Drug-induced gingival overgrowth is a well-established adverse event. In early stages, this gingival enlargement is usually located in the area of the interdental papilla. Histologically, there is an increase in the different components of the extracellular matrix
%K Fibroblast
%K Collagen
%K Drug-induced gingival overgrowth
%K Growth factor
%K Cellular cultures
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564016/