%0 Journal Article
%T Her2/neu Protein Expression and Oncogene Amplification in Gastric Carcinoma with Clinico-Pathological Correlation in Egyptian Patients
%A Ahmed Abdel Hadi
%A Ahmed Sadek
%A Ali El Hindawi
%A Amal Hareedy
%A Amgad Anas
%A Heba Khalil
%A Hisham Bakr
%A Mona Magdy
%A Olfat Hammam
%A Rafatt Atta
%A Ranya Al Ashiry
%A Shady Elia
%J Archive of "Open Access Macedonian Journal of Medical Sciences".
%D 2016
%R 10.3889/oamjms.2016.104
%X Amplification of the Her2/neu gene and overexpression of the Her2/neu protein in gastric carcinoma (GC) is a golden criterion for target therapy with trastuzumab (Herceptin). We aim to evaluate the immunohistochemical protein expression and amplification of the oncogene Her2/neu by FISH technique in the epithelial gastric carcinoma and to compare their association with different clinicopathologic parameters aiming at identifying positive cases that may benefit from targeted therapy
%K Her2/neu
%K Gastric carcinoma
%K immunohistochemistry
%K fluorescence in situ hybridization
%K dysplasia
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175495/