%0 Journal Article
%T Pretreatment Effect of Folic Acid on 13-Cis-RA-Induced Cellular Damage of Developing Midfacial Processes in Cultured Rat Embryos
%A Rungarun Kriangkrai
%A Sachiko Iseki
%A Suconta Chareonvit
%A Visaka Limwongse
%J Archive of "The Open Dentistry Journal".
%D 2017
%R 10.2174/1874210601711010200
%X Excess treatment of 13-cis-RA (Accutane£¿) on pregnant women induces craniofacial malformation found in infants. However, the effect of folic acid on 13-cis-RA-induced cellular damages of developing midfacial processes is still unknown. The purpose of this study was to investigate the pretreatment effect of folic acid (FA) on 13-cis-RA-induced cellular damage in developing midfacial processes in rat embryos
%K Apoptosis
%K Cell proliferation
%K Folic acid
%K Midfacial process
%K 13-Cis-RA
%K Rat embryo
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418950/