%0 Journal Article %T Modeling Associations between Chemosensation, Liking for Fats and Sweets, Dietary Behaviors and Body Mass Index in Chronic Smokers %A Brittany A. Larsen %A Mark D. Litt %A Tania B. Huedo-Medina %A Valerie B. Duffy %J Archive of "Nutrients". %D 2019 %R 10.3390/nu11020271 %X Chronic smokers have a greater risk for altered chemosensation, unhealthy dietary patterns, and excessive adiposity. In an observational study of chronic smokers, we modeled relationships between chemosensation, fat/carbohydrate liking, smoking-associated dietary behaviors, and body mass index (BMI). Also tested in the model was liking for sweet electronic cigarette juice (e-juice). Smokers (n = 135, 37 ¡À 11 years) were measured for: Taste genetics (intensity of 6-n-propylthiouracil¡ªPROP); taste (NaCl and quinine intensities) and olfactory (odor identification) function; liking for cherry e-juice; and weight/height to calculate BMI. Smokers survey-reported their food liking and use of smoking for appetite/weight control. Structural equation models tested direct and indirect relationships between chemosensation, fat/carbohydrate liking, dietary behaviors, and BMI. In good-fitting models, taste intensity was linked to BMI variation through fat/carbohydrate liking (greater PROP intensity¡úgreater NaCl intensity¡úgreater food liking¡úhigher BMI). Olfactory function tended to predict sweet e-juice liking, which, in turn, partially mediated the food liking and BMI association. The path between smoking-associated dietary behaviors and BMI was direct and independent of chemosensation or liking. These findings indicate that taste associates with BMI in chronic smokers through liking of fats/carbohydrates. Future research should determine if vaping sweet e-juice could improve diet quality and adiposity for smokers %K sweet liking %K fat liking %K e-cigarettes %K body mass index %K dietary behaviors %K smell %K taste %K tobacco %K cigarettes %K chronic smoking %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412709/