%0 Journal Article
%T High-altitude Pulmonary Hypertension: an Update on Disease Pathogenesis and Management
%A Aibek E. Mirrakhimov
%A Kingman P. Strohl
%J Archive of "The Open Cardiovascular Medicine Journal".
%D 2016
%R 10.2174/1874192401610010019
%X High-altitude pulmonary hypertension (HAPH) affects individuals residing at altitudes of 2,500 meters and higher. Numerous pathogenic variables play a role in disease inception and progression and include low oxygen concentration in inspired air, vasculopathy, and metabolic abnormalities. Since HAPH affects only some people living at high altitude genetic factors play a significant role in its pathogenesis
%K Altitude physiology
%K cardiac failure
%K epidemiology
%K treatment
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780514/