%0 Journal Article
%T Improvement of Triglyceride Levels through the Intake of Enriched-¦Â-Conglycinin Soybean (Nanahomare) Revealed in a Randomized, Double-Blind, Placebo-Controlled Study
%A Hiroki Satoh
%A Jun Nishihira
%A Makita Hajika
%A Mie Nishimura
%A Tatsuya Ohkawara
%A Yoko Takahashi
%A Yuji Sato
%J Archive of "Nutrients".
%D 2016
%R 10.3390/nu8080491
%X Soybean is recognized as a beneficial food with various functional components, such as ¦Â-conglycinin, which improves lipid metabolism. We evaluated the effects of the ¦Â-conglycinin-rich soybean Nanahomare on triglyceride (TG) levels. In this randomized, double-blind, placebo-controlled study, we divided 134 adult subjects into test and placebo groups that consumed processed food containing enriched-¦Â-conglycinin soybean or low-¦Â-conglycinin soybean. Hematological tests and body composition measurements were performed at weeks 0 (baseline), 4, 8, and 12 of the study period. TG levels significantly decreased in the test group compared with the placebo group at weeks 4 (change from baseline to week 4, placebo: 0.27 ¡À 44.13 mg/dL, test: £¿20.31 ¡À 43.74 mg/dL, p = 0.035) and 12 (change from baseline to week 12, placebo: £¿0.14 ¡À 65.83 mg/dL, test: £¿21.30 ¡À 46.21 mg/dL, p = 0.041). In addition, among subjects whose baseline TG levels were ¡Ý100 mg/dL, the levels significantly improved in the test group at weeks 4 (p = 0.010) and 12 (p = 0.030), whereas the levels were not different between the test and placebo groups among those whose baseline levels were <100 mg/dL. These results suggest that the ingestion of enriched-¦Â-conglycinin soybean improves serum TG levels
%K clinical trial
%K Nanahomare
%K soybean
%K triglyceride
%K ¦Â-conglycinin
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997404/