%0 Journal Article %T Irbesartan Induced Cutaneous Melanoma! Second Case in the Medical Literature! %A Georgi Tchernev %A Ivanka Temelkova %J Archive of "Open Access Macedonian Journal of Medical Sciences". %D 2019 %R 10.3889/oamjms.2019.043 %X Drug-induced melanoma is a topic, concept or ˇ°realityˇ± becoming more and more popular as the list of drugs considered as potential inducers of cutaneous melanoma is constantly growing. Interesting and current at the moment is the question/dilemma of ˇ°Irbesartan induced melanomasˇ± and ˇ°Valsartan induced melanomasˇ±! The following questions are without answers: 1) the general risk which angiotensin receptor blockers contain for potentiating the carcinogenesis and cancer development (as a whole); 2) available officialized data for withdrawal from the market of products with valsartan and irbesartan due to detected potential carcinogens-NDMA/NDEA, and 3) the missing official information on the most likely forms of cancer potentiated by these drugs. That is precisely why many questions remain open, and the inevitable assumption arises for the key, although according to some conspiratorial role of so-called ˇ°pharmaceutical giantsˇ± in the concept of drug-induced malignancies %K Irbesartan %K ARB %K Drug-induced melanoma %K Surgery %K Survival benefit %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352483/