%0 Journal Article %T Effectiveness of Platelet Rich Plasma and Bone Graft in the Treatment of Intrabony Defects: A Clinico-radiographic Study %A Ipsita Jayanti %A Jayachandran Mahesh %A Krishna Kripal %A Mohamed Faizuddin %A Mohammad Jalaluddin %A Nazia Nazeer %A Rethi Mahesh %J Archive of "The Open Dentistry Journal". %D 2018 %R 10.2174/1874210601812010133 %X Periodontal disease is characterized by the presence of gingival inflammation, periodontal pocket formation, loss of connective tissue attachment and alveolar bone around the affected tooth. Different modalities have been employed in the treatment and regeneration of periodontal defects which include the use of bone grafts, PRP and other growth factors.The purpose of this prospective, randomized controlled study was to compare the regenerative efficacy of PRP and bonegraft in intrabony periodontal defects %K Bone graft %K Infrabony defects %K Periodontal regeneration %K PRP. Platelet Derived growth factors (PDGF) %K Epithelial growth factor (EGF) %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883369/