%0 Journal Article
%T Glucose homeostasis dependency on acini¨Cislet¨Cacinar (AIA) axis communication: a new possible pathophysiological hypothesis regarding diabetes mellitus
%A Jaros£¿aw Woli¨½ski
%A Kateryna Goncharova Pierzynowska
%A Peter C. Gregory
%A Rafa£¿ Filip
%A Stefan G. Pierzynowski
%J Archive of "Nutrition & Diabetes".
%D 2018
%R 10.1038/s41387-018-0062-9
%X a Balanced Acini¨Cislet¨Cacinar (AIA) feedback maintains sustainable glucose utilization by insulin-independent (muscle, fat, etc.) and amylase-dependent glucose assimilation (gut tissues, gut bacteria). b The overstimulation of the pancreas enlarges the AIA defensive mechanism against the hyperglycaemic condition; c exhaustion of the acinar cells leads to the development of functional exocrine pancreatic insufficiency and hyperglycemia as a consequenc
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174155/