%0 Journal Article %T Investigating the accuracy, risk impact, and cost-effectiveness of component-resolved diagnostic test for food allergy: a systematic review protocol %A Andrew Stoddart %A Aziz Sheikh %A Bright I. Nwaru %A Javier Flores Kim %A Nicola McCleary %J Archive of "NPJ Primary Care Respiratory Medicine". %D 2017 %R 10.1038/s41533-017-0015-0 %X Food allergy¡ªparticularly immunoglobulin E (IgE)-mediated food allergy¡ªis now a global public health problem. It results in considerable morbidity, healthcare utilisation, and impairment in quality of life.1¨C6 Food allergy reactions range in severity from relatively mild features to life-threatening anaphylaxis.2, 3 Estimates of the prevalence of food allergy vary, but overall lifetime prevalence has been estimated as affecting up to 7% of children and 6% of adults.4, %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434809/