%0 Journal Article
%T Magnetofluorescent Nanocomposite Comprised of Carboxymethyl Dextran Coated Superparamagnetic Iron Oxide Nanoparticles and ¦Â-Diketon Coordinated Europium Complexes
%A Daewon Han
%A Do Kyung Kim
%A Hwan-Woo Park
%A Jongdae Shin
%A Nam Seob Lee
%A Seung-Yun Han
%A Young Gil Jeong
%J Archive of "Nanomaterials".
%D 2019
%R 10.3390/nano9010062
%X Red emitting europium (III) complexes Eu(TFAAN)3(P(Oct)3)3 (TFAAN = 2-(4,4,4-Trifluoroacetoacetyl)naphthalene, P(Oct)3 = trioctylphosphine) chelated on carboxymethyl dextran coated superparamagnetic iron oxide nanoparticles (CMD-SPIONs) was synthesized and the step wise synthetic process was reported. All the excitation spectra of distinctive photoluminesces were originated from f-f transition of EuIII with a strong red emission. The emission peaks are due to the hypersensitive transition 5D0¡ú7F2 at 621 nm and 5D0¡ú7F1 at 597 nm, 5D0¡ú7F0 at 584 nm. No significant change in PL properties due to addition of CMD-SPIONs was observed. The cytotoxic effects of different concentrations and incubation times of Eu(TFAAN)3(P(Oct)3)3 chelated CMD-SPIONs were evaluated in HEK293T and HepG2 cells using the WST assay. The results imply that Eu(TFAAN)3(P(Oct)3)3 chelated CMD-SPIONs are not affecting the cell viability without altering the apoptosis and necrosis in the range of 10 to 240 ¦Ìg/mL concentrations
%K europium complexes
%K superparamagnetic
%K iron oxide nanoparticles
%K magnetofluorescent
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359550/