%0 Journal Article %T IL-6 and the dysregulation of immune, bone, muscle, and metabolic homeostasis during spaceflight %A John Kelly Smith %J Archive of "NPJ Microgravity". %D 2018 %R 10.1038/s41526-018-0057-9 %X Effect of body weight on IL-6 production by cultured peripheral blood mononuclear cells. This figure is from a publication on the effect of long-term exercise on peripheral blood mononuclear cell (PBMC) production of osteoclastogenic and anti-osteoclastogenic cytokines.4 a Spontaneous production of IL-6 by cultured PBMC (N£¿=£¿41 subjects). b IL-6 production in PBMC cultures containing the T-cell mitogen phytohemagglutinin (PHA) (N£¿=£¿41 subjects). c IL-6 production by PBMC of women in PHA£¿+£¿cultures (N£¿=£¿23 subjects). d IL-6 production by PBMC of men in PHA£¿+£¿cultures (N£¿=£¿18 subjects). (Linear regression analyses with 95% confidence intervals %U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279793/