%0 Journal Article
%T Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides
%A Charles D. Brilliant
%A David W. Thomas
%A Elaine L. Ferguson
%A Georgina E. Menzies
%A Jack M. Copping
%A Kate A. Powell
%A Katja E. Hill
%A Lydia C. Powell
%A Manon F. Pritchard
%A Niklaas J. Buurma
%A Paul D. Lewis
%A Phil D. Rye
%A Shree U. Patel
%A Stavroula-Melina Sakellakou
%J Archive of "NPJ Biofilms and Microbiomes".
%D 2018
%R 10.1038/s41522-018-0056-3
%X Effect of OligoG on inhibition of mucoid biofilm formation: Imaging and quantification of P. aeruginosa (NH57388A) biofilms grown for 24£¿h at 37£¿¡ãC in MH broth£¿¡À£¿OligoG (0.5%, 2% & 6%). a SEM imaging of biofilms (Scale bar, 10£¿¦Ìm). b CLSM 3D imaging (aerial view) of LIVE/DEAD£¿ staining of biofilms (Scale bar, 20£¿¦Ìm). c COMSTAT image analysis of the corresponding biofilm CLSM z-stack images. *P£¿<£¿0.05 significance was determined by comparison to the untreated control. Error bars represent the standard deviation of the data set (n£¿=£¿3
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026129/