%0 Journal Article
%T Investigating the relationships between hypothalamic volume and measures of circadian rhythm and habitual sleep in premanifest Huntington's disease
%A Alpar S. Lazar
%A Alvaro Reyes
%A Anthony J. Hannan
%A Danielle M. Bartlett
%A James A. Slater
%A Juan F. Dom¨ªnguez D
%A Kirk W. Feindel
%A Mel Ziman
%A Pauline Zaenker
%A Peter R. Eastwood
%A Robert U. Newton
%A Travis Cruickshank
%J Archive of "Neurobiology of Sleep and Circadian Rhythms".
%D 2019
%R 10.1016/j.nbscr.2018.07.001
%X Pathological changes within the hypothalamus have been proposed to mediate circadian rhythm and habitual sleep disturbances in individuals with Huntington¡¯s disease (HD). However, investigations examining the relationships between hypothalamic volume and circadian rhythm and habitual sleep in individuals with HD are sparse. This study aimed to comprehensively evaluate the relationships between hypothalamic pathology and circadian rhythm and habitual sleep disturbances in individuals with premanifest HD
%K Huntington¡¯s disease
%K Hypothalamus
%K Magnetic resonance imaging
%K Circadian rhythm
%K Sleep
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586591/