%0 Journal Article
%T (99m)Tc-MIBI Uptake in a Thyroid Adenoma with Diffuse Adipose Metaplasia
%A Fabrizio Fasolini
%A Gaetano Paone
%A Giuseppe Peloni
%A Luca Giovanella
%A Luca Mazzucchelli
%J Archive of "Nuclear Medicine and Molecular Imaging".
%D 2016
%R 10.1007/s13139-015-0383-8
%X A 71-year-old female underwent a (99m)Tc-MIBI scan to characterize a cold nodule (30 mm) of the left thyroid lobe. The nodule showed diffuse uptake and retention of the radiotracer. After resection, histological examination demonstrated a microfollicular adenoma with diffuse white adipose metaplasia. Although mitochondria in brown adipose tissue have been widely studied, we have only a limited understanding of the relevance of mitochondria in white adipose tissue. Active mitochondria are present in white adipocytes, and this may account for the MIBI uptake, mimicking a hyperproliferation pattern, in our patient
%K Tc MIBI
%K Thyroid
%K Adenoma
%K Adipocyte
%K Metaplasia
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135689/