%0 Journal Article
%T Bullous dermatosis suspected in an 8-month-old child in Guinea-Bissau
%A Ana Paula Arias
%A Beatriz Valle del Barrio
%A Danila Luraschi
%A Laurent Hiffler
%A Robert Micheletti
%J Archive of "Oxford Medical Case Reports".
%D 2019
%R 10.1093/omcr/omz004
%X An 8-month-old child was admitted to a paediatric intensive care unit in Guinea-Bissau with severe blistering dermatosis. He was treated with broad spectrum antibiotics and dressings, without improvement. After 2 weeks, linear IgA bullous dermatosis was suspected. Owing to lack of dapsone, the child was treated with prednisolone and improved. To avoid corticosteroids side effects, 2 months after starting prednisolone we switched to colchicine, but the boy¡¯s condition worsened for reasons of poor adherence, requiring intravenous corticosteroids and antibiotics. After complete resolution of the skin lesions, we continued with colchicine monotherapy, then changed to dapsone after 3 months. The child did not show any further signs of dermatosis, but his follow-up ended abruptly, because he did not return to the hospital. IgA bullous dermatosis is a challenging diagnosis in settings where pathological studies cannot be conducted. Multidisciplinary treatment is required and colchicine is a good option if dapsone is not available
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464016/